Soy Isoflavones


Soy, a staple food in many Asian countries, contains valuable constituents, including protein, isoflavones, saponins, and phytosterols. The isoflavones in soy, primarily genistein and daidzein, have been well researched by scientists for their antioxidant and phytoestrogenic properties.

Clinical Applications

Cancer prevention

  • Inhibit most types of hormone-dependent and hormone-independent cancer cell lines in vitro, including colon cancer.


  • Helpful in reducing the hot flashes of menopause.

Pre-menstrual syndrome

  • Serve as partial estrogen agonists or antagonists.
  • Reduces the effects of excess estrogens associated with premenstrual syndrome (PMS) by antagonizing the interaction of these hormones with their receptors.


  • Induce a reduction in bone resorption caused by diminished post-menopausal levels of estrogens.

How Does It Work?

Anti-cancer effects

  • Combinations of soy isoflavones have demonstrated their usefulness as chemo-protective agents relative to urinary bladder cancer in vitro and in vivo.
    • Cancer cell growth is arrested, enzyme systems indicative of malignant activity are inhibited, and apoptosis (cell suicide) in cancer cells is induced without altering cell cycle distribution.
  • Inhibit breast cancer cell proliferation in vitro.
  • May reduce the risk of prostate cancer.

Hormonal effects

  • Express moderate hormonal effects in post-menopausal women.
  • Manifest no effect on the menstrual cycle, serum sex hormones, or urinary estrogen metabolite ration in premenstrual women, regardless of whether they are using oral contraceptives.

Bone metabolism

  • There is evidence that genistein binds weakly to estrogen receptor-alpha, the receptor found on hormone-responsive tissue in a woman’s organs, and strongly to estrogen receptor-beta, the receptor found on bone. This concept can explain the apparent of protection against cancer and bone loss.


Typical dosage is 50-100 mg daily.

Side Effects

Caution should be exercised with patients who have known sensitivity to soy products. In rare cases, there may be an enhancement or diminution in thyroid output.

To order soy isoflavones by phone, please call toll-free 877-347-8600.