From C.A.M. Report
Comparing fructose- and glucose-sweetened beverages
Overweight and obese subjects consumed glucose- or fructose-sweetened beverages, and researchers from the US and Japan compared the effects.
A new TV commercial in the US claims there’s no difference. Not so, according to these results. Here are the findings, and the potential significance of this research.
First, the details.
* 32 overweight and obese adult men and women were observed for 10 weeks.
* They drank beverages sweetened with glucose or fructose that accounted for 25% of their daily calorie intake.
And, the results.
* Participants in both groups put on about the same amount of weight.
* Fasting triglyceride blood levels increased 10% with glucose but not with fructose.
* Changes recorded with fructose only
o Increased belly fat
o Production of fat by the liver
+ aka hepatic de novo lipogenesis (DNL)
o Increased markers of altered lipid metabolism (eg, apoB, LDL [bad] cholesterol)
o Increased concentrations of remnant-like particleâ€”triglyceride and â€”cholesterol
+ Newly proposed risk factors for heart disease
o Increased fasting blood sugar and insulin levels
o Decreased insulin sensitivity
The bottom line?
The authors concluded, “Dietary fructose specifically increases DNL, promotes dyslipidemia, decreases insulin sensitivity, and increases visceral adiposity in overweight/obese adults.”
An accompanying editorial provides perspective. “While these symptoms are telltale signs of metabolic syndrome, which raises a person’s risk of heart attack, we still don’t know what the long term implications of fructose consumption on such a risk might be.”